ADJ
- addictive, carcinogenic, dangerous, harmful, hazardous, noxious, poisonous, radioactive, toxic
- innocuous
- Even innocuous substances can sometimes register a positive result in a drug test
- banned, illegal
- natural
- a natural substance found in the body of animals
- chemical
- inorganic, organic
- pure
- soluble, volatile
- crystalline, fatty, oily, slimy, sticky, viscous
- medicinal
VERB + SUBSTANCE
- use
- contain
- produce
- Some frogs produce very toxic substances in their skin
- take
- The athletes had taken banned substances to increase their strength
ADJ
- real
- The real substance of the report was in the third part
- added
- His disappearance has given added substance to the argument that he stole the money
VERB + SUBSTANCE
- have
- The image of him that the media have presented has no substance
- give sth, lend sth
- The letters lent substance to the rumours
- lack
PREP
- in ~
- There's no difference in substance between the two points of view
- of ~
- Nothing of substance was achieved at the meeting
- without ~
- Their allegations were without substance
- ~ in
- There's no substance in the story
- ~ to
- There was little substance to his claims
